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Tuesday, 6 October 2015

Alzheimer

Know about  Alzheimer : Causes and  Symptoms



Alzheimer's disease
This is a disease with the basic symptom of Dimentia, that is loss of memory in the patients,  the patient might feel difficulty in remembering recent events , though memories of old past are intact.
Gradually the patient might show one or all of these symptoms,
               1)         Trouble focussing
               2)      Feeling Confused or frustrated
               3)      Dramatic Mood Swings
               4)      Unable to cope with Societal affairs
               5)      Feeling disoriented and getting lost very often
               6)      Trouble Communicating
               7)      Disturbed Co-ordination in physical activities like walking



The disease makes brain tissue break down, and occurs generally after the age of 65 , and females are more prone to this disease.

Causes of Alzheimer's disease

Scientists believe generally two types of nerve damages in brain are the main reasons of Alzheimer's disease.
              1)      Tangling of nerves, called neurofibrillary tangles.
              2)      Protien deposits  called  beta amyloid plaques




                               
Scientists are not sure, why are the potential reasons of this damage , but the possible reasons could be the presence of a protein in blood called  ApoE, ie; apoliprotein E, which is used by the body to move cholesterol in the blood.

But recently,  a multi institutional team led by scientists of Indiana University, including one Scientist of Indian origin, have discovered an immune system gene called 1RAP, associated with higher risks of amyloid plaque, building up in the brains of Alzheimer's  patients. And found that it had even greater effects than well-known ApoE protein.

There is some evidence that, peole with high blood pressure and high cholesterol have a greater chance of getting Alzheimer's later in life.
Scientists are still studying the causes and possible cure of this disease , and as far as now, old age and genetical history of Alzheimer's in your ancestors had been known as the two main risks of getting this disease.


Though no potential cures have been discovered for this disease till now,  but scientifical studies are going on to find the effective therapies for this disease.

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